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CHARLOTTE, NORTH CAROLINA - MARCH 16: Joanne Verkuilen In blue dress with belt, and Susan Cooke, in blur top with white pattern, are sisters who run Circle+Bloom (http://www.circlebloom.com/), an e-commerce business that looks at the connection between the mind and body to help women with fertility issues. The company has no traditional office, but the sisters live in the Charlotte, N.C., area, within about 10 minutes of each other. (Photo by Peter Taylor)